Q&A with Nephrologist Tara Chang

March 7, 2025 - by Rebecca Handler

March is National Kidney Month, a time to raise awareness about kidney health and the steps we can take to prevent kidney disease. We chatted with Tara Chang, MD, MS, Division Chief of Stanford Nephrology, to discuss the biggest risk factors and early warning signs of the disease, and the latest advancements in research. 

What are the biggest risk factors for kidney disease, and how can they be managed?

The biggest risk factors for kidney disease are high blood pressure, diabetes, and obesity. The good news is that managing these conditions can help protect your kidneys. Eating a healthy diet, staying active, and taking the right medications can make a big difference. Some medications not only help control blood pressure and blood sugar but also have extra benefits for kidney health.

What are some early warning signs of kidney disease that people often miss?

Kidney disease is often a "silent" condition, meaning most people don’t know they have it until it’s in a late stage. In fact, many people with kidney disease have no idea they’re affected. There can be a few warning signs, like high blood pressure or changes in urine color, but most of the time, the only way to catch it early is through simple lab tests.

Why is early screening for kidney disease so important, and who should get tested?

People at higher risk for kidney disease should get screened, which includes anyone with high blood pressure, diabetes, obesity, or a family history of kidney disease.

A recent study from Stanford also suggested that screening everyone over age 35 could help people live longer, prevent kidney failure, and be a worthwhile investment in health. Right now, the US Preventive Services Task Force is reviewing whether to officially recommend broader kidney disease screening.

What recent advancements in kidney research or treatment are you most excited about, and how might they impact patient care?

We’re in an exciting time for kidney research. After nearly 20 years without anything new, there are now breakthrough therapies that can slow kidney disease and help people avoid dialysis or a transplant.

In the past, we only had a couple of types of medications—ACE inhibitors and ARBs—that we knew could help slow down kidney disease. But now, we have newer drugs like SGLT2 inhibitors and finerenone that not only protect the kidneys but also support heart health. There are even new treatments designed specifically for a type of kidney disease called IgA nephropathy, and many more promising options are being developed. It’s an exciting time for kidney care!

That’s why getting checked for kidney disease is more important than ever—catching it early means you can take steps to protect your kidneys and stay healthier longer.